Regamo Vaginal Ovules Brand New, Sealed in Box 100% Authentic, Made in Italy. Each Box contains 10 ovules. Usage Directions: This product needs to be stored in the refrigerator for 30 mins to 1 hour before using. Wash hands before using, Place 1 ovule vaginally before going to bed. Storage: Protect from sunlight and store between 5 and 25 degrees Celsius. USA Seller, we ship within 2 business days excluding holidays and weekends. Message us with any questions.